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Fig. 4. Comparison of XLMO-2, GATA-1 and SCL expression patterns. RNA in situ hybridization analysis reveals that these genes have very similar expression patterns. Each gene is expressed at a high level in the VBI. GATA-1 expression is restricted to erythrocytes whereas SCL and XLMO-2 are also expressed in other embryonic tissues such as the brain and tailbud.