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Fig. 1. Morphological features of Emx2-/-Otx2+/- double mutant brains. (A,E,I,M) Wild-type, (B,F,J,N) Otx2+/-, (C,G,K,O) Emx2-/- and (D,H,L,P) Emx2-/-Otx2+/- embryos. (A-D) Sagittal sections stained with Cresyl Violet, (E-H) frontal sections stained with Cresyl Violet and (M-P) sagittal sections stained with Hematoxylin and Eosin. (I-L) Dorsal views of embryos. (A-H) 15.5 dpc, (I-P) 12.5 dpc. Arrows in A-D indicate the position of posterior commissure; circles in I-L indicate cerebral hemispheres. cb, cerebellum; cp, choroid plexus; Di, diencephalon; dt, dorsal thalamus; ept, epithalamus; hip, hippocampus; hp, hypophysis; ht, hypothalamus; ic, inferior coliculus; lge, lateral ganglionic eminence; ma, mammillary region; Me, mesencephalon; met, metencephalon; mge, medial ganglionic eminence; ncx, neocortex; ob, olfactory bulb; opc, optic chiasma; pt, pretectum; s, septum; spc, superior coliculus; Te, telencephalon; tg, tegmentum; vt, ventral thalamus; 3v, the third ventricle. Scale bars: 500 µm.