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Fig. 8. Midbrain phenotype in knock-in mutants. (A,C,E,G,I,K) Wild-type and (B,D,F,H,J,L) knock-in mutant embryos. (A,B) Wnt1, (C,D) Ebf3, (E,F) COUP-TFI, (G,H) En1, (I,J) Pax5 and (K,L) Fgf8 expression at 9.5 dpc (K,L) and 10.5 dpc (A-J). Scale bars: 125 µm.