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Fig. 3. Treatment with PKI{alpha} antisense oligonucleotides suppressed right sided expression of SnR. Examples of SnR expression in embryos treated at stage 4 with sense (A) and antisense (B) oligonucleotides. Dorsal views at stage 9 are shown. Note that SnR signal is symmetrical within somites. Suppression of SnR signal by AS treatment is seen most prominently in the posterior area of lateral mesoderm. Black arrowheads point to areas of high expression and white arrowheads point to areas of low expression.