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Fig. 4. Sequence specificity of antisense oligonucleotides. Percentages of embryos exhibiting bilateral expression of Nodal following treatments with oligonucleotides. Values below treatments represent the number of embryos with bilateral Nodal expression/ the number of embryos treated with oligonucleotides. The nucleotide sequences of oligonucleotides are shown in inset. Mismatches with chick PKI{alpha} are underlined. AS, antisense; S, sense.