Fig. 9. Vertebrate Otx2 genes contain a conserved element within the 3' UTR. (A) Schematic alignment between the mouse and the human, chicken, Xenopus, zebrafish, lamprey and Amphioxus Otx2 3' UTRs, showing the conserved 140 bp element. Percentages of homology between corresponding regions are reported with different colours. In lamprey, only 26 bp of the element are conserved. (B) Percentages of identity of the 140 bp element among the reported gnathostomata. (C) DNA sequence alignment of the conserved element, also including the 26 bp conserved sequence of the lamprey.