Development -- Gavalas et al. 128 (15): 3017 Figure IG3

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Fig. 3. Mitotic and cell death patterns in the second pharyngeal arch are not altered despite the loss of ncc. Wild-type (a,d), Hoxa1^-/- (b,e) and Hoxa1^-/-/Hoxb1 3'RARE^-/- (c,f) embryos were processed for whole-mount immunohistochemical detection of mitosis (a-c) and cell death (d-f). (a-c) Reduced but considerable mitotic activity was still detected in the second pharyngeal arch (pa2) of both Hoxa1^-/- and Hoxa1^-/-/Hoxb1 3'RARE^-/- embryos. (d-f) There was no increase of cell death in the second pharyngeal arch of either Hoxa1^-/- or Hoxa1^-/-/ Hoxa1^-/- Hoxb1 3'RARE^-/- embryos.