
Fig. 5. L1 is not involved in the migration of cortical GABAergic interneurons. The broken line demarcates the ventricle. Arrows point to streams of GABA-immunopositive cells. The migration of MGE cells was examined in cortical slice cultures in the presence (A) or absence (B) of L1 Fab fragments. Immunostaining against TAG-1 in cryostat sections of E14.5 wild-type (C) and L1 mutant (D) mouse brains. Immunostaining against GABA in cryostat sections of E14.5 wild-type (E,G) and L1 mutant (F,H) mouse brains. Scale bars: 100 µm in A-D; 110 µm in E,F; 55 µm in G,H.