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Fig. 8. Normal dephosphorylation of arylsulfatase A in LAP/Acp5-deficient fibroblasts. Control (Lap/Acp5+/+) and doubly deficient (Lap/Acp5–/–) mouse embryonic fibroblasts were labelled for 6 hours with [35S] or [32P]arylsulfatase A and subsequently chased with non labelled medium up to 24 hours. The disappearance of the labelled arylsulfatase A is followed and the ratio of [32P]/[35S]arylsulfatase A is calculated indicating normal dephosphorylation of arylsulfatase A.