Fig. 7. UO126 blocks FGF-induced cell elongation in lens explants. Representative scanning electron micrographs of cells in explants cultured for 5 days in the absence of FGF2 (A,B) or with 100 ng/ml of FGF2 (C,D) in the presence of DMSO (A,C) or DMSO with UO126 (B,D). FGF2 induced the elongation of lens epithelial cells (C, arrows). In the presence of UO126, this elongation could be blocked (D), with cells demonstrating a similar morphology to cells in control explants (A,B). Scale bar: 5 µm.