Development -- Long et al. 128 (24): 5099 Figure IG2

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Fig. 2. Removal of Smo reduces the growth of long bones. (A) A comparison of E18.5 limb skeletons of wild type, Smo conditional null and Ihhⁿ/Ihhⁿ embryos. FL, forelimb; HL, hindlimb. (B) Relative lengths of E18.5 long bones of Cre10; Smoⁿ/Smo^c embryos compared with Ihhⁿ/Ihhⁿ and wild-type bones. T, tibia; F, fibula; U, ulna; H, humerus; S, scapula; n=7. (C) Growth of the limbs at postnatal day 3 (P3) and P9 in Cre10; Smoⁿ/Smo^c (MT) versus wild-type (WT) mice.