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Fig. 3. (A) Representative histological sections from the bow region of wild-type (+/+) and {alpha}8 homozygous knockout (–/–) lenses. The arrows indicate the lens bow region where epithelial cells differentiate to become fiber cells. Scale bar, 50 µm. (B) Double immunolabeling of {alpha}8 (red) and {alpha}3 (green) connexins in the cortical fibers of the frozen sections from wild-type (+/+) and {alpha}8 homozygous knockout (–/–) lenses. Scale bar, 5 µm.