
Fig. 6. lacZ expression patterns in the lenses of
3 and
8 knockout mice. (A) A side view of an eye, stained for ß-gal, from an
8 heterozygous (+/) knockout mouse. The lens equator is indicated by an arrow and anterior monolayer epithelium is blue. C, cornea; R, retina; O, optic nerve. B and C show lenses from adult
8+/ and
3+/ sibs, respectively, stained for ß-gal; anterior view. (D) An equatorial view of the
3+/ lens in C; an arrow indicates the lens equator. (E-G)
8+/, wild-type (+/+) and
3+/ embryos at 14 dpc, respectively. (H-J) Magnified views of eyes of the embryos in E, F and G, respectively. Scale bars (A-G) 1 mm; (H-J) 250 µm.