Fig. 5. The cdl-1 gene. (A) Domain structures of CDL-1 and related proteins. The RNA stem-loop binding domain (striped boxes) are shared by all four proteins. Other domains conserved in the vertebrate proteins are not found in CDL-1. (B) Sequence alignment of the RNA binding domain of CDL-1 with human (hSLBP), mouse (mSLBP), Xenopus (xSLBP1) and Drosophila (dSLBP) SLBPs. The mutated residues in e2510 (P-to-S missense mutation) and e2501 (nonsense mutation) are indicated. (C) Structure of the cdl-1 ORF. The mutation sites in e2510 and e2501 and the deleted region in w37 are indicated. The neighboring predicted ORFs are also shown.