Fig. 1. Expression of Eda (Ta, encoding the TNF ectodysplasin) and Edar (dl, encoding the TNF receptor Edar) during hair follicle development in the back skin. (A,B) Eda and Edar transcripts are co-expressed in the E12 embryonic ectoderm. (C-F) At E14-15, Eda expression continues in the ectoderm except in the newly formed placodes. The placodes express Edar intensely, whereas it is downregulated in the rest of the ectoderm. (G-H) Eda and Edar transcripts are intensely expressed in the bulb of newborn stage 3-6 hair follicles. Eda expression continues in the epidermis. Scale bar: 100 µm.