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Fig. 8. The effect of anti-eSRS21 antibody treatment on spermatogonial proliferation using a germ-somatic cell co-culture system. (A,B) Microphotographs show the pellets of germ cells/somatic cells cultured with anti-eSRS21 IgG and IgG from normal rabbit serum, respectively. GA and GB indicate type A spermatogonia and late type B spermatogonia, respectively. Scale bar: 50 µm. (C) The rate of appearance of proliferated germ cells (late type B spermatogonia). IC, initial controls; C, controls; 11KT, 11-ketotestosterone; anti-eSRS21, anti-eSRS21 IgG. Results are given as the mean±s.e.m. Values with the same lowercase letter(s) are not significantly different (P<0.05).