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Fig. 11. Sacral-to-vagal heterotopic graft, E8. (A) Numerous transplanted sacral cells (arrowheads) were present external to the circular muscle layers, in the region corresponding to the myenteric plexus. (B) In the intestine, sacral cells were evident within the myenteric plexus (mp) external to the circular muscle. Occasional QCPN+ cells were present in the submucosal plexus region (smp) (arrowheads). (C) No transplanted sacral NC-derived cells were observed in the colorectum at this stage of development. Scale bars: 100 µm.