Development -- Roman et al. 129 (12): 3009 Figure IG2

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Fig. 2. Disruption of acvrl1 increases the number of endothelial cells in the basal communicating artery (BCA) and posterior connecting segments (PCS) at 2-2.25 dpf. (A,B) Representative confocal micrograph of the central cranial vasculature of (A) a vbg⁺;TG(fli1;nEGFP)^y7 wild-type embryo, and (B) a vbg^ft09e;TG(fli1;nEGFP)^y7 mutant embryo. The greater than two-fold increase in endothelial cell number in the BCA/PCS in vbg^ft09e embryos compared to wild-type embryos is significant at P<0.00001. BA, basilar artery. Dorsal views, anterior to the left.