Development -- Marino et al. 129 (14): 3513 Figure IG5

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Fig. 5. Immunoblotting of protein extracts from cerebella of L7cre; Pten^LoxP/LoxP, L7cre; Pten^LoxP^/+ En2cre; Pten^LoxP/LoxP and wild-type mice. Increased levels of phospho-Akt are only detected when Pten is deleted on both alleles in Purkinje cells (L7cre; Pten^LoxP/LoxP mice) or in all cells of the vermis (En2cre; Pten^LoxP/LoxP), while wild-type and L7cre; Pten^LoxP^/+ cerebella show no difference.