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Fig. 2. (A) Comparison of eve-class homeodomain sequences from lophotrochozoans (Hro, Helobdella robusta; Ttr, Theromyzon trizonare), cnidarians (Afo, Acropora formosa; Nve, Nematostella vectensis), deuterostomes (Bfl, Branchiostoma floridae; Dre, Danio rerio; Mmu, Mus musculus; Hsa, Homo sapiens; Xla, Xenopus laevis) and ecdysozoans (Cel, Caenorhabditis elegans; Dme, Drosophila melanogaster; Sam, Schistocerca americana; Tca, Tribolium castaneum). Two similar non-eve-class homeodomain sequences are included for comparison (HmHD, Hirudo medicinalis homeodomain protein; Dmpb, Drosophila melanogaster proboscipedia). Consensus amino acid residues are highlighted, and amino acid residues flanking known intron sites are underlined. Values in parentheses indicate the percentage amino acid identity with Hro-eve.