Fig. 1. her1 and her7 are included in the b567 deficiency and b567 mutant embryos have somitic defects. (A,B) Dorsal view of embryos hybridized with an in situ hybridization screen cocktail including pax2, forkhead6, floating head, valentino and her1. (A) Wild-type embryo; (B) b567 mutant embryo lacking her1 expression (arrows). (C,D) Although somite formation is disrupted in b567 mutant embryos (D) as compared to wild-type embryos (C), overall embryo morphology is normal at this stage. (E) Map of the b567 deficiency. A total of 25 markers, including SSLPs (z-markers), ESTs (prefixed by fa, fb and fc), and cloned genes (italicized), were PCR-amplified from DNA prepared from b567⁺ and b567^– embryos. Markers that failed to amplify from b567^– DNA samples are indicated in red. Map positions are indicated in cM (indicating relative position on the integrated map [ZMAP] that includes all 6 independent mapping panels) and in cR (indicating position on the T51 mapping panel, on which 18 of the tested 25 markers have been mapped). Approximate centromere position is indicated by a thick black box. The solid red line indicates the extent of the deficiency and the dashed red line indicates the possible location of the telomeric breakpoint. The b567 deficiency deletes approximately 92-174 cR (15-22 cM) of LG 5.