Fig. 7. Repulsion by Dephrin depends on DEph. (A,B) Injection of dsGFP RNA (A) increases the severity of the axonal phenotype caused by ectopic Dephrin in midline cells (compare with 6A). Commissures are often lost completely. In contrast, lowering the expression of DEph by DEph RNAi (B) allows axons (red) to cross over ectopic midline sources of Dephrin (green). Injection of dsDEph RNA into embryos with ectopic midline expression of Dephrin frequently restores the axonal scaffold to normal. Horizontal views of stage 17 embryos; anterior to the left.