Development -- Raetzman et al. 129 (18): 4229 Figure IG5

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 5. Proliferation in Rathke’s pouch at E12.5 and E14.5 is unaffected in mice lacking Prop1, Lhx4, or in double mutants. Immunostaining of BrdU-injected embryos was performed to assess proliferation levels in the pituitary mutants at E12.5 (A-D) and at E14.5 (E-G). Wild-type (A,E), Prop1^df/df (B,F), Lhx4^–/– (C,G) and Prop1^df/dfLhx4^–/– (D) mice all had dividing cells in the pituitary primordium. The anterior lobe is indicated with a bracket.