Fig. 2. Analysis of ectopic cell division and distribution of cleavage orientation in wild-type and Pax6^Sey/Sey cortex at E10.5, E12.5 and E15.5. (A) Histogram showing the mean percentage (±s.e.m.) of late anaphase and telophase cells that are dividing in an ectopic postion (away from the ventricular surface) in wild-type cortex and Pax6^Sey/Sey cortex. There is an increase in ectopic division at E15.5 in the mutants(P<0.0005). (B,C) Graphs comparing the mean percentages of dividing cells undergoing symmetrical, asymmetrical and intermediate division in (B) wild-type and (C) Pax6^Sey/Sey cortex. All data points are ±2%.