Fig. 1. A map of the eve locus is shown at the top. The positions of five enhancers that control early stripe formation (1-7) are shown. Two other enhancers that control the refinement of the initial stripes (LE), and later expression in inter-stripe regions (ftz-like) are also indicated. A map of the eve 2 minimal stripe element (MSE) is shown in the middle with positions of defined binding sites for transcription factors. Activator and repressor sites are closely linked, especially in two clusters, each of which contains two pairs of overlapping sites. Regions tested by deletion analyses are marked (D1-D5). A model for eve 2 regulation is presented at the bottom. Activation is mediated by Bcd and Hb, while Gt and Kr are involved in repression mechanisms that form the stripe borders.