Fig. 6. Morphological defects in the developing telencephalon of the Pax6^-/- mice revealed with Nissl staining. (A-C) Nissl-stained coronal section of an E14.5 wild-type brain showing a normal cortical lamination (B) and the morphology of the PSPB (arrowheads in C). (D-F) In Pax6^-/- brain, an expanded ventricular zone (vz) and a thinner cortical plate (cp) (arrows in E) was observed. Note the absence of cp in the lateral pallium (arrow in F). ctx, cerebral cortex; LV, lateral ventricle; mz, marginal zone. Scale bars: 200 µm in A,D; 100 µm in B,C,E,F.