Fig. 2. Mutations in CSN5 cause eggshell defects. (A) A wild-type eggshell. Note the length of the dorsal appendages (DA) and the separation at their bases. (B-F) Eggshells derived from females carrying CSN5-mutant, germline clones. (B,C) Fused or absent DA in weakly or strongly ventralized eggshells. (D) A partially dorsalized eggshell. Bases of the appendages are more widely separated than in wild type. (E) Short but normally spaced DA. (F) An unusual eggshell with duplicated DA. In addition to these eggshell defects, some eggs had an unusually weak eggshell. These eggs were sometimes destroyed during attempts to move them. This phenotype may be related to observations made during dechorionation or fixation that many eggs from CSN5 GLC mothers fall into pieces.