Development -- Herbst et al. 129 (23): 5449 Figure IG8

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 8. The synaptic zone remains broader in Musk^-/-; MCK-Musk and Musk^-/-; MCK-MMT adult mice. As a consequence of delayed expression from the MCK gene, the axon termination zone is wider in MCK^-/-; MCK-Musk and MCK^-/-; MCK-MMT embryos than in wild-type embryos, and this broader termination zone is retained in adult mice. Wholemounts of diaphragm muscles from 3-week-old mice were stained with antibodies to neurofilament (NF) and synaptophysin (Syn) to label axons and presynaptic nerve terminals (green), and with Texas-Red ${alpha}$ -Bungarotoxin (TR- ${alpha}$ -BGT) to label AChRs (red).