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Fig. 4. shar-pei mutant cells upregulate Cyclin E levels. (A-C) shrp1 mutant clones in the eye disc marked by the absence of GFP expression (red) stained for Cyclin E (green). (C) merged channels. Cyclin E is upregulated in cells of shrp mutant clones (arrows), in particular posterior to the SMW (arrowhead).