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Fig. 4. Normal preplate splitting in Dab1p45/– hemizygotes. Immunhistochemical detection of chondroitin sulphate proteoglycan (CSPG) in saggital sections of E16.5 brains. (A) Dab1p45/–, (B) Dab1–/+, (C) Dab1p45/p45 and (D) Dab1p45/+ littermate brains. Arrowheads indicate CSPG staining of marginal zone and subplate. Scale bar: 200 µm.