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Fig. 3. Defects in differentiation of bile duct epithelial cells in J1N2+/– and Notch2del1/Notch2del1 mice. (A-D) DBA-stained sections of livers at P0. (A) Wild-type mouse. (B) J1N2+/– littermate of wild-type mouse in A. (C) Wild-type mouse. (D) Notch2del1/Notch2del1 littermate of wild-type mouse in C. Almost no DBA-positive cells (arrows in A and C) are observed in either the J1N2+/– or the Notch2del1/Notch2del1 mice. pv, portal vein.