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Fig. 1. Gug mutations act as dominant suppressors of a tsh reporter gene in the eye. (A,B) Heterozygotes for P(Lac w+)tshJ834 (B is also heterozygous for the GugS2 mutation). (A) Note that the white gene is active in anterior cells of the eye (Sun et al., 1995) as is the tsh gene; (B) expression of these genes is reduced.