Fig. 6. Adult eye development in 2-day-old metatrochophora larvae. Apical views at 48 hours of development. Expression of pax6 (A) six1/2 (B) and r-opsin (C) in the growing adult eye. Black arrowheads indicate isolated dorsal cells constantly expressing pax6. (D) Schematic drawing of gene expression patterns at 48 hours of development. Natural pigment (brown spots) serves as morphological landmark. Abbreviations: ae, adult eyes; le, larval eyes; oa, optic anlagen; oc, optic commissure; ant, antennae; plp, palpae anlagen.