
Fig. 10. Histology of RUNX1-CBF2T1-related intracranial hemorrhages. Hematoxylin and Eosin staining of sagittal head sections at 48 hpf. Control is indicated. Arrows in A and B indicate intraventricular and intracerebral hemorrhages, respectively. (D,E) Higher magnifications of areas boxed in A,B respectively, with arrows indicating areas of bleeding. In D, an associated small intracerebral hemorrhage is shown (arrowhead). (F) At higher magnification, immature erythroid cells were present within hemorrhages (arrow). Scale bars:
50 µm.