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Fig. 2. Molecular structure of smp-1 and smp-2 genes and their predicted protein products. (A) The K14B11 cosmid carries smp-1. Regions deleted in ev708 and ev715 are indicated under the summary of exon/intron structure of the appropriate gene. (B) The smp-1 cDNA is aligned with the predicted protein Ce-Sema-1a. The D1037 cosmid carries smp-2. The region deleted in ev709 is indicated. The smp-2 cDNA is aligned with the predicted protein Ce-Sema-1b. Predicted domains within the proteins are as indicated: signal sequence (purple), semaphorin domain (yellow), Furin protease consensus cleavage site (green), Met related sequence (MRS) (blue), transmembrane domain (black) and a predicted PDZ binding domain (red).