Fig. 3. Size reduction and loss of otic vesicles in fish injected with Fgf3 and Fgf8 morpholinos. (A-E) 26 hour (prim 8) embryos photographed at the same magnification using Nomarski optics. Where otic vesicles are present (arrows), their maximum diameter (anteroposterior axis) is measured and indicated in red. (A) Embryo injected with control Fgf3 morpholino. (B) Embryo injected with Fgf3mo. (C) Embryo injected with Fgf8mo. (D,E) Embryos co-injected with Fgf3mo and Fgf8mo showing further reduced size (D) or absence of an otocyst (E).