Fig. 4. Detection of apoptotic and dividing cells in embryos injected with Fgf3 and Fgf8 morpholinos. Apoptotic (A-L) and dividing cells (M-T) detected in lateral views of zebrafish embryos at 14 somites photographed at low and high magnification (A-H) and in dorsal views of the hindbrain and otic territory of embryos at 8 somites (I-T). (A,B,I) Embryos injected with control Fgf3 morpholino. (C,D,K) Embryos injected with Fgf3 morpholino. (E,F,J) Embryos injected with Fgf8 morpholino. (G,H,L) Embryos injected with both Fgf3 and Fgf8 morpholinos; note large number of apoptotic cells in the dorsal midline of the neural tube in 14 somite embryos. (M-T) Low magnification (M,O,Q,S) and high magnification (N,P,R,T) views of dividing cells in the hindbrains and adjacent otic territory of embryos injected with both control morpholinos together (M,N), Fgf3 morpholino (O,P), Fgf8 morpholino (Q,R) and Fgf3mo together with Fgf8mo (S,T).