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Fig. 1. Jun is required for axial skeletogenesis. (A) Skeletal phenotype of Bal1;Jun{Delta}/{Delta} mice. Photograph of an adult Bal1;Jun{Delta}/{Delta} and Junf/f control littermate. Arrowhead indicates scoliosis. (B,C) Alcian Blue/Alizarin Red skeletal preparations of E18.5 Bal1;Jun{Delta}/{Delta}-mutant (C) and Junf/f control (B) embryos. Arrow in C indicates fused atlas and axis. (D,E) Dorsal view of Alcian Blue stained E16.5 Bal1;Jun{Delta}/{Delta}-mutant (E) and Junf/f control (D) mice. The epidermis and the neural tube were removed to visualise vertebral cartilage. Arrowheads in E indicate fusions of Alcian Blue-positive domains.