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Fig. 1. Mutations in spr-3 and spr-4 potently suppress the egg-laying defect of sel-12 mutants. The percentage of animals that exhibit a protruding vulva (Pvl, black bar), an egg-laying defect (Egl, gray bar) and that die of internal hatching (Bag, white bar) are shown for the wild-type (N2), sel-12 and three separate alleles each of spr-3 and spr-4 in a sel-12(ar171) background. Number of animals examined: N2, 100; ar171, 95; by108, 97; by109, 99; by110, 99; by105, 92; by130, 95; by132, 87.