Fig. 3. Wnt1 reporter and misexpression transgene constructs. (A)
Schematic of Wnt1 promoter (Wnt1p) and gene under control of
the strong 1.1 kb enhancer that contains a point mutation in HBS1 (mHBS1)
(Iler et al., 1995). (B) The
lacZ reporter transgene driven by
HBS1 regulatory sequences.
(C) The Wnt1-Tg misexpression transgene driven by
HBS1
regulatory sequences. For descriptions, see text.