Fig. 6. Rhombomere and cranial ganglion patterning in RA-rescued Raldh2^–/– embryos. (A-D) Hoxa2 and kreisler rhombomeric transcript patterns were analyzed in E8.5 wild-type (A,C) and Raldh2^–/– (B,D) embryos (dorsal views). (E,F) Analysis of Ret transcripts, which mark the prospective cranial ganglia NCCs in E9.5 wild-type embryos (E), reveals a selective deficiency of the 9th and 10th ganglion cells in mutant embryos (F, a bracket indicates the few post-otic Ret-labeled cells). ot, otocyst; r2-r6, rhombomeres; 7-8, 9, 10, prospective cranial nerve ganglia.