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Fig. 6. A model for GLD-1 and glp-1 mRNA regulation in the early embryo. In posterior cells, GLD-1 binds to the GRE, probably with other factors (not shown), and represses glp-1 mRNA translation. In anterior cells, a derepressor (D) binds to the GDE to inhibit GLD-1 binding or activity, leading to glp-1 translation. Localization of glp-1 translation is further ensured by enrichment of GLD-1 in posterior cells.