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Fig. 6. Immunohistochemistry for BrdU to visualize the number of mitotically active cells in the epidermis. Samples at low magnification (A,C) and high magnification (B,D) of E16.5 wild-type (A,B) and K5-Klf4 DTs (C,D) reveal a decrease in proliferation in the transgenic mice. The dotted line indicates the basement membrane.