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Fig. 5. (A) Left: two Cerebratulus lacteus oocytes with ER clusters before roscovitine addition. Right: 60 minutes after roscovitine treatment. (B) Roscovitine-induced disassembly of ER clusters and polar body (pb) formation in C. lacteus. Timing from left to right: before roscovitine, and 5 minutes, 10 minutes, 15 minutes and 30 minutes post-treatment. (C, right) A Cerebratulus sp. oocyte that spontaneously progressed through metaphase I arrest and formed polar bodies (pb). Note lack of ER clusters compared with metaphase-I-arrested cohort (left). Scale bars: 50 µm.