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Fig. 3. hnd-1 morphogenesis defect. (A,C,E) wild type, (B,D,F) hnd-1(q740). (A) Wild-type L1 with normal body morphology. The gonadal primordium is bracketed. Three cells are visible: Z1, black arrow; PGCs, white arrows; Z4 is in a different focal plane. (B) hnd-1 L1 with typical body shape defect (black arrow). Arrested larvae often have vacuoles in the head (arrowheads). (C) Wild-type pretzel-stage embryo is elongated and contains pharynx (ph) and gut. (D) hnd-1 pretzel-stage embryo has not elongated posteriorly (arrow), but has a fully developed pharynx and gut tissue, which can be disorganized. (E) Wild-type embryos stained with {alpha}-myosin antibodies. Two muscle quadrants are visible in this plane (arrowheads). (F) hnd-1 embryos generate four muscle quadrants, which can be disorganized posteriorly (arrow); three quadrants are visible in this plane (arrowheads). Scale bar: 10 µm.