Fig. 5. Co-expression of dpp and eya rescues photoreceptor
differentiation and furrow progression in smo mutant clones. (A-H)
Each set of three panels in A-H depicts the same disc containing large
smo clones stained for anti ß-galactosidase (red), Anti-Elav
(green) or a merge of the two. The ey-GAL4 driver was used to induce
transgene expression in all cases. (A-D) Neither dpp (A,C) nor
eya (B,D) expression alone can rescue the loss of photoreceptor
differentiation in posterior margin smo clones (A,C) or the slowing
of furrow progression in internal smo clones (arrows in B,D). (E,F)
Posterior margin smo clones expressing both dpp and
eya differentiate photoreceptors as visualized by Elav
immunoreactivity (arrow in E). Furrow progression is not delayed in internal
smo clones expressing dpp and eya (arrow in F).
(G,H) Similarly, co-expression of dpp, eya and so also
rescues photoreceptor differentiation and furrow progression in smo
clones, often inducing ectopic furrows from anterior smo clonal areas
(arrows in G,H).