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Fig. 7. spenDN acts downstream of Arm stabilization. Micrographs are SEMs of adult fly heads from flies containing P[GMR-Gal4], P[GMR-arm*]F36 and either P[UAS-lacZ] (A) or P[UAS-spenDN]II (B) reared at 25°C. Expression of an activated form of Arm activates Wg signaling and produces an eye that is severely reduced in size and is suppressed by P[UAS-spenDN].