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Fig. 5. swi1-2 mutation suppresses the dif1-1 chromosome fragmentation phenotype. (A) Metaphase I in a wild-type male meiocyte. Five bivalents are observed. (B) dif1-1 meiocyte exhibiting chromosome fragmentation. (C) swi1-2 meiocyte at the end of prophase. Twenty chromatids are observed. (D,E) swi1-2/dif1-1 double mutant meiocytes. (D) Sister chromatid cohesion is lost at the end of prophase I. (E) The resulting 20 free chromatids at metaphase I. (F) Some cells contained 10 condensed univalents. Scale bar: 10 µm.