Fig. 3. Homozygous ceh-2(ch4) mutants are retarded in larval development. (A) Duration of larval development in wild type (N2) and ceh-2(ch4). (B) Rescue of the slow growth defect by a ceh-2 transgene. Most ceh-2(ch4) mutants take more than 51 hours to develop into adults. Worms carrying the genomic rescue transgene pTRB203 develop faster. The error bar represents the s.d. of four independent transgenic strains; less than wild-type rescue of ceh-2(ch4) is probably due to a slight growth disadvantage of the rol-6D co-injection marker used.