(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.



Fig. 6. DMKP3 functions both in the R3/R4 pair and outside of the photoreceptors. (A) A section through a mosaic eye and a magnification and further examples of mosaic ommatidia in insets. Pigmented cells are Dmkp3+ (arrowheads), tissue devoid of pigment granules is Dmkp3-. Cartoons represent the genotype with Dmkp3+ photoreceptors in red and Dmkp3- cells in pink. (B) Quantitative analysis of 73 phenotypically Dmkp3- mosaic ommatidia (cartoons to the left, compare to Fig. 5A) showing both Dmkp3- (pink in the bar diagram) and Dmkp3+ photoreceptors (red) at any position. Data are from both males and females and absolute numbers are given above and below the chart, respectively. Genetically wild-type ommatidia exhibiting a Dmkp3- shape can also be observed close to a Dmkp3- clone (section through a male eye in C and insets). (D) Concordantly, an additional photoreceptor (blue) can differentiate into an R4 cell (red) even outside of a Dmkp3- clone (marked by the absence of GFP, green) (higher magnification in E-H). The misdifferentiated cell is marked by an arrow. R4 cells (red) are also observed outside of ommatidial clusters (green) in a sevS11 background (arrow in I-K) providing an explanation for the occurrence of extra outer photoreceptors in sevS11 eye-sections (arrow in L).